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Tao Jiang
Professor
Computer Science and Engineering
330 Surge Building
University of California
Riverside, CA 92521
Phone: (951) 827-2991
Fax: (951) 827-4643



Areas of Expertise
  • Computational Molecular Biology
  • Bioinformatics
  • Combinatorial Algorithms

 Background
Research Interests
Selected Publications (Bibliography Page)
Current Laboratory Personnel

Background:

I received a B.S. in Computer Science and Technology from the University of Science and Technology of China , Hefei, P.R.China in July 1984 and a Ph.D., in Computer Science, from the University of Minnesota in Nov. 1988. During Jan. 1989 - June 2001, I was a faculty member at Department of Computing and Software, McMaster University, Hamilton, Ontario, Canada. During 1995-96, I took a research leave at University of Washington , Seattle, and at Gunma University , Kiryu, Japan. I joined University of California - Riverside as a Professor of Computer Science in Sept. 1999.

I have published in many theoretical computer science and bioinformatics/computational biology journals and served on program committees of many international conferences and workshops including The 15th IEEE International Conference on Tools with Artificial Intelligence (ICTAI 2003), The 14th Annual International Symposium on Algorithms and Computation (ISAAC 2003), The 31st International Colloquium on Automata, Languages and Programming (ICALP 2004), Research in Computational Molecular Biology (RECOMB) International Conference (RECOMB 2004), The IEEE Fourth Symposium on Bioinformatics and Bioengineering (BIBE 2004), and The IEEE Computational Systems Bioinformatics Conference (CSB 2004).

I am presently serving on the editorial boards of Journal of Bioinformatics and Computations Biology (JBCB), International Journal of Foundations of Computer Science (IJFCS) , Journal of Combinatorial Optimization (JOCO) , and Journal of Computer Science and Technology (JCST) .

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Research Interests

Design and analysis of algorithms.

We study discrete objects such as strings, trees, graphs, etc., and have a special interest in the design of efficient approximation algorithms with good performance bounds. Our recent work includes approximation algorithms for shortest common superstrings and directed Steiner trees. We are also working on an average-case analysis technique by the incompressibility method, which is based on Kolmogorov complexity. Our recent results incldue average-case analyses of algorithms for a wide range of problems including sorting, majority, matrix multiplication, random walk, communication complexity, and problems in geometry.

Computational molecular biology.

We are interested in developing efficient algorithms and software for sequence alignment, phylogenetic analysis, and DNA microarray design. Our recent work includes polynomial-time approximation schemes for tree alignment, efficient algorithms for comparing annotated sequences, a heuristic for block based multiple sequence alignment, an approximation scheme for quartet-based reconstruction of evolutionary trees, a technique for efficiently clean quartet errors, and a few prototype software tools. From THIS PAGE you can download a prototype of our integrated multiple sequence alignment and phylogenetic reconstruction system on X-Window (called TAAR V1.0 ). Here is the homepage of our software for computing combined DNA and protein alignment (called DPA ). Your feedback is certainly welcome.

I am presently collaborating with Ming Li, Mike Clegg, James Borneman, and Francey Sladek, on efficient and robust algorithms for the reconstruction of phylogenies, comparative plant genomics, high throughput clone screening using DNA microarray, and the identification of transcription factor binding sites. Here is the home page of the computational biology research group at University of Waterloo, McMaster University, and Queen's University, funded by the Canadian Genome Analysis and Technology Program (CGAT) and Communication and Information Technology Ontario (CITO). My current research is funded by NSF CCR, NSF ITR, and NSF DBI programs.

If you are interested in learning the abc of computational biology and bioinformatics, you may find some useful educational material and reference material on the subjects. The DOE Primer on Molecular Genetics contains helpful information on the Human Genome Project and the field of genomics. Our book Current Topics in Computational Molecular Biology has recently been published by the MIT Press as a part of its Computational Molecular Biology Series (and co-published by Tsinghua Univ. Press in China). A list of the topics covered in the book can be found here.

Selected Publications (Bibliography Page)

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Current Laboratory Personnel

  • Xin Chen (postdoc)
  • Petr Kolman (postdoc)
  • Andres Figueroa (graduate student)
  • Jing Li (graduate student)
  • Jie Zheng (graduate student, joint with Stefano Lonardi)
  • Zheng Liu (graduate student)
  • Haifeng Li (graduate student)
  • Zheng Fu (graduate student)
  • Qing Zhang (graduate student)
  • Chuhu Yang (Genetics graduate student, joint with Frances M. Sladek)

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