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CEPCEB Members
Background I received my Ph.D. Degree jointly from the Electrical and Computer Engineering Department and the Bioengineering Department of the University of California, San Diego in 2001. My two master's degrees are from Stanford University and the University of Illinois at Urbana Champaign in the fields of materials science and electrical engineering. An advocate of interdisciplinary studies, I have used my own rich, interdisciplinary background to fabricate DNA or live-cell microarrays using electric fields or optical forces inside a sealed-chip arrangement. This new platform is developed for highthroughput drug screening or phenotyping applications. Once cellular arrays are formed by electrical forces, micromanipulation of cells within the array is achieved by using multi-beam micro lasers. Currently, I am the director of the Biomedical Science and Nanotechnology Laboratory at the School of Engineering in UCR. My research interests include the development of biomedical microdevices and applications of nanotechnology for future developments in bioengineering. I put extra emphasis on a multi-disciplinary education from K to the graduate level. I established new courses and workshops at various levels for the training of the future's "multi-lingual" scientists. Some of my synergistic activities include participation in Conference organizations in the field of Biotechnology and Bio-micro-electro-mechanical systems (BioMEMS), and membership in the Board of Trustees for the International Society for BioMEMS and Biomedical Nanotechnology. Some of my career awards include: the Regents' Faculty Award (2002), the Graduate Student Award from the Jacobs School of Engineering, San Diego (2002 and 2001), the Bio-Medical Engineering Society, Seattle (2000), and the Materials Research Society, Boston (2000 and 1999). Related to bio-nanotechnology, I also hold a large number of patent disclosures of which many are licensed by Biotech-companies.
Biological-micro-mechanical-systems (Bio-MEMS), Bio-Photonics and Lab-on-a-chip Platforms Our research includes the development of novel biological-micro-mechanical-systems (Bio-MEMS) and the exploration of engineering principles in the field of Bio-Photonics for applications in bioengineering. My interdisciplinary background previously helped to fabricate an electrically and optically addressable micro-device to address and array optoelectronic devices on silicon based circuits and live cells on a sealed-chip arrangement (http://www.soe.ucsd.edu/news_events/Recognition_Awards/). Similarly, the design of multi-functional, smart and complex systems such as lab-on-a-chip platforms that require the integration of optical, electrical, chemical, biological and fluidic (mechanical) components constructed from dissimilar materials summarizes our primary interest. To convey multi-functionality, individual processing units need to be miniaturized to micro or nano scale. This procedure may not be trivial and cannot be easily scaled down. It can require massive engineering analysis and characterization of each processing unit in terms of mechanical, thermal, electrical stability and biological compatibility. Finally, miniaturized processing units need to be heterogeneously integrated on the same platform. As a summary, my laboratory centers on the development of novel physical and engineering principles to miniaturize each processing unit and also focuses on the development of new heterogeneous integration methods to fabricate lab-on-a-chip systems for chemical and/or bioengineering applications.
Selected Publications (Bibliography Page) | ||||||||||
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